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KMID : 0390320110210010137
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Chungbuk Medical Journal
2011 Volume.21 No. 1 p.137 ~ p.145
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Amplitude-Integrated Electroencephalography in the Low Birth Weight Infant Who Have Apnea that Not Responded to Treatment
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Kim Yoo-Jin
Sim Ji-Yun
Kim Mi-Jung
Lim Gin-A
Kim Won-Seop
Lee Ji-Hyuk
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Abstract
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Purpose:To assess the value and the limitations of aEEG (amplitude integrated electroencephalography) for screening tool in comparison with EEG (electroencephalography) in neonates who were suspected of having seizure in NICU (neonatal intensive care unit).
Materials and Methods :We retrospectively studied 11 preterm infants less than 1500 g who had been suspected of seizure on NICU from January 2009 to February 2010. The infants had apnea that did not respond to aminophyline or a continuous positive airway pressure. And we compared aEEG with EEG, echoencephalography and phenobarbital treatment effect.
Results:The aEEGs showed seizure pattern in 5 (45.4%), flat pattern in 1 (9.2%), and normal pattern in 5 (45.4%). In 5 patients with seizure pattern of aEEG, repetitive seizure pattern was showed in 4, single seizure pattern in 1. In 5 patients with normal aEEG, echoencephalography showed normal pattern in 3 (60.0%), germinal matrix hemorrhage Grade I in 1 (20.0%), germinal matrix hemorrhage Grade IV in 1 (20.0%). There was no correlation between aEEG and EEG (P value=0.764).
Conclusion:
The results of aEEG and EEG were not correlated. aEEG is not useful to screen the seizure or neurophysiology in place of EEG.
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KEYWORD
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aEEG, Apnea, Low birth weight infant
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